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Potential Noninvasive Wet AMD Treatments, Fuchs Dystrophy Genetic Link, Technology Obstacles

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In this week's EyewireTV, the INTREPID study, which examined Oraya Therapeutics’ radiation therapy for the treatment of wet AMD, has met its primary endpoint; and research confirms that a genetic factor is a strong predictor of an individual’s risk of developing Fuchs dystrophy. In the weekly feature, industry and venture capital executives share their thoughts on overcoming the challenges involved in bringing new technology to the marketplace.

VEGF Trap-Eye Improves Vision in Diabetic Eye Disease

From Medscape Ophthalmology

Vascular Endothelial Growth Factor (VEGF) Trap-Eye provided a significant benefit to patients with diabetic macular edema in a phase II trial - and updated data now shows the initial improvements were sustained or increased a year later. The 24-week results of the DA VINCI study, published in 2011, showed that VEGF Trap-Eye intravitreal injections ...

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Thursday, May 17, 2012

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NovaBay Enrolls First Patients in Global BAYnovation Phase 2...

From NovaBay Pharmaceuticals, Inc. — 5/17/2012

NovaBay Pharmaceuticals, Inc., announced that it has enrolled the first patients in its global Phase 2b clinical study. The study (named BAYnovation) ...Full story

Smartphones Can Help the Visually Impaired, but Many Doctors...

From Loyola University Health System — 5/17/2012

iPhones and other smartphones can be a huge help to the visually impaired, but few vision doctors are recommending them to patients, according to a st...Full story

Lutein, Zeaxanthin May Reduce Cataract Risk: Study

From Nutra Ingredients — 5/17/2012

Lutein and Zeaxanthin may protect the lens of the eye from oxidative stress and reduce the risk of cataract, says a new study. The protective effect o...Full story

Optical Coherence Tomography Useful for Macular Edema

From Medscape Today — 5/17/2012

In patients with diabetic macular edema, visual acuity (VA) correlates with the magnitude of change in central macular thickness (CMT). The strongest ...Full story

Wednesday, May 16, 2012

Eye Cancer Tumors Likely To Spread Can Be Identified By Gene...

From Medical News Today — 5/16/2012

Researchers at Washington University School of Medicine in St. Louis have developed a genetic test that can accurately predict whether the most common...Full story

Can PlusoptiX Replace Cycloplegic Exams in Young Children?

From Medscape Ophthalmology — 5/16/2012

Do children who have had undilated plusoptiX exams also need to have dilated exams to make sure that abnormalities have not been overlooked? That is t...Full story

Genentech to Test Alzheimer's Drug on Healthy Patients in Hi...

From Oakland Tribune — 5/16/2012

Roche's Genentech unit has won the right to try its experimental Alzheimer's drug crenezumab on people with no signs of dementia -- the first such tri...Full story

Docs Win Most Malpractice Cases at Trial

From Medpage Today — 5/16/2012

Plaintiffs hardly ever win medical malpractice cases that go all the way to a jury verdict, and only 4.5% of claims filed ever go that far, researcher...Full story

Tuesday, May 15, 2012

Pacific Cataract and Laser Institute Sees Big Benefits with ...

From Pacific Cataract and Laser Institute — 5/15/2012

Anoto and NextGen Healthcare Information Systems LLC announced that Pacific Cataract and Laser Institute is capturing new patient registration informa...Full story

Vision Loss Due To Degenerative Eye Diseases May Be Restored...

From Medical News Today — 5/15/2012

Using tiny solar-panel-like cells surgically placed underneath the retina, scientists at the Stanford University School of Medicine have devised a sys...Full story

Topical Antibiotics Boost Risk of Endophthalmitis After Eye ...

From Medscape Today — 5/15/2012

After intravitreal injections of anti-vascular endothelial growth factors or triamcinolone, topical antibiotics might actually be unhelpful, a new pap...Full story

Changes in Eye Vessels Signal Heart Troubles

From Medpage Today — 5/15/2012

Changes in diameter of the tiny blood vessels in the retina predicted the later development of cardiovascular disease in African Americans with type 1...Full story

Carl Zeiss Meditec Continues its Profitable Growth

From Carl Zeiss Meditec AG — 5/15/2012

Medical technology provider Carl Zeiss Meditec generated growth of 14.8% in the first six months of financial year 2011/2012. The company posted reven...Full story

Eye Changes May Predict Heart Disease in Blacks With Diabete...

From US News & Health Report — 5/15/2012

In black Americans with type 1 diabetes, narrowing of the small arteries in the eye's retina (retinal arteriolar narrowing) is associated with increas...Full story

Monday, May 14, 2012

Bausch + Lomb Names John Barr Global President Surgical

From Bausch + Lomb — 5/14/2012

Bausch + Lomb has named John Barr Global President of the company's surgical business. In this capacity, Mr. Barr will oversee the company's full suit...Full story

New Advances In Treating Inherited Retinal Diseases

From Medical News Today — 5/14/2012

Gene therapy strategies to prevent and treat inherited diseases of the retina that can cause blindness have progressed rapidly. Positive results in an...Full story

Two Glaucoma Implants Equally Good at 3 Years

From Medscape Today — 5/14/2012

The Ahmed glaucoma valve and the Baerveldt glaucoma implant, the 2 most commonly used glaucoma drainage implants in the United States, are equally suc...Full story

Lights On or Off for Pediatric Red Reflex Exam?

From Medscape Ophthalmology — 5/14/2012

Pediatricians detect ocular disease in infants and children using the red reflex exam, but does it underestimate the presence of that disease? That's ...Full story

FDA Grants Fast Track Designation to Ohr Pharmaceutical's Sq...

From Ohr Pharmaceutical — 5/14/2012

Ohr Pharmaceutical Inc. announced that its Squalamine Eye Drops, a potent inhibitor of multiple growth factors implicated in angiogenesis, has been aw...Full story

New Type of Retinal Prosthesis Could Better Restore Sight to...

From Stanford University Medical Center — 5/14/2012

Using tiny solar-panel-like cells surgically placed underneath the retina, scientists at the Stanford University School of Medicine have devised a sys...Full story

Friday, May 11, 2012

Optos Continues to Demonstrate Strong Clinical Evidence

From Optos PLC — 5/11/2012

Optos PLC announced the presentation of more than 50 positive clinical studies at ARVO. The clinical studies involved clinical sites from 49 academic ...Full story

Besifloxacin Demonstrated Potent Activity, High Rate of Erad...

From Bausch + Lomb — 5/11/2012

The antibiotic besifloxacin demonstrated potent activity and high rates of eradication against problematic multi-drug resistant organisms that cause e...Full story

Advanced Loteprednol Etabonate Gel Formulation May Offer New...

From Bausch + Lomb — 5/11/2012

Bausch + Lomb announced that its new loteprednol etabonate (LE) gel formulation demonstrated safety and efficacy for the treatment of ocular inflammat...Full story

Amakem Appoints Dr. Steve Pakola as Chief Medical Officer; D...

From Amakem NV — 5/11/2012

Amakem NV, a kinase platform company focusing on ophthalmology, today announces the appointment of Dr. Steve Pakola as Chief Medical Officer and Dr. G...Full story

Thrombogenics: Announces Business Update

From 4-Traders — 5/11/2012

ThromboGenics signed an important strategic deal with Alcon, the global leader in eye care, to commercialize ocriplasmin outside the U.S. ThromboGenic...Full story

High-Dose Ranibizumab No Better Than Standard Dose for AMD

From Medscape Today — 5/11/2012

High-dose ranibizumab (Lucentis) does not provide better visual acuity than standard-dose ranibizumab in newly diagnosed wet age-related macular degen...Full story

Researchers Present Data Highlighting Potential of Peregrine...

From Peregrine Pharmaceuticals, Inc. — 5/11/2012

Peregrine Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company developing first-in-class monoclonal antibodies for the treatment and diag...Full story

Thursday, May 10, 2012

Seven Scientific Posters Sponsored by TearScience at ARVO Ad...

From TearScience, Inc. — 5/10/2012

TearScience Inc. announced that it sponsored research for seven scientific posters on evaporative dry eye and its technology at ARVO. Subjects reflect...Full story

Ista Pharmaceuticals Highlights Prolensa Clinical Data at AR...

From Ista Pharmaceuticals Inc. — 5/10/2012

Ista Pharmaceuticals, Inc. presented results from the second of two phase 3 studies of Prolensa (bromfenac ophthalmic solution), the company's once-da...Full story

Topical Aganirsen Found To Be Active In Retinal Disease

From Medical News Today — 5/10/2012

Gene Signal, a company focused on developing innovative drugs to manage angiogenesis based conditions, has announced that positive data from a study o...Full story

Retinopathy Screenings Can Be Less Frequent

From Medscape Today — 5/10/2012

Screening for retinopathy every 2 years instead of the recommended annual screening would be safe and could reduce screening costs by about 25% for pe...Full story

Bill Would Repeal SGR, Phase Out Medicare Fee-for-Service

From Medscape Today — 5/10/2012

A bipartisan bill introduced in the House today would avert a Medicare pay cut of roughly 30% in 2013 by repealing the program's sustainable growth ra...Full story

Hoya Reports Fourth Quarter and Full-Year Financial Results

From Hoya — 5/10/2012

Hoya Corp. announced financial results for the fourth quarter and full-year ended March 31, 2012. For the quarter under review, revenues from all oper...Full story

Retinal Microchip Restores Vision in Retinitis Pigmentosa

From Medscape Today — 5/10/2012

A subretinal microchip implant has entered new clinical trials in the United Kingdom and Hong Kong, and early results are encouraging, according to re...Full story

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